HIGH DOSE CHEMOTHERAPY AND AUTOLOGOUS BONE MARROW TRANSPLANTATION FOR ADVANCED GERM CELL TUMOR
نویسندگان
چکیده
منابع مشابه
Successful salvage high-dose chemotherapy and autologous stem-cell transplantation in HIV-related germ-cell tumor.
Testicular germ-cell tumors (GCT) occur more frequently in human immunodeficiency virus (HIV)-infected patients than in the general population [1]. Initial studies indicated that the outcome of patients with HIV-related GCT was poor compared with those without HIV infection [2, 3]. Nevertheless, since the introduction of highly active antiretroviral therapy the outcome has improved due to a dec...
متن کاملSuccessful treatment of refractory Hodgkin's disease by high-dose combination chemotherapy and autologous bone marrow transplantation.
Forty-four patients with refractory Hodgkin's disease were treated with high-dose combination chemotherapy followed by autologous bone marrow rescue. Twenty-two patients (50%) entered complete remission within 6 months of the procedure and four other patients are free of disease progression. Only two patients have subsequently relapsed from complete remission (CR). Bone marrow suppression was t...
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We evaluated the pharmacokinetics and pharmacodynamics of filgrastim during a Phase I study of this cytokine following high-dose chemotherapy and autologous bone marrow transplantation. Serum granulocyte colony-stimulating factor concentrations were determined by ELISA in 21 patients receiving 14-day continuous i.v. filgrastim infusions and 10 patients receiving daily 4-h infusions. Models were...
متن کاملHigh-dose chemotherapy and autologous bone marrow transplantation in acute myeloid leukemia.
For younger patients with acute myeloid leukemia (AML), an allogeneic transplant from a matched sibling may afford the best chance of cure. In patients who are older or without a matched sibling donor, dose intensification can be achieved with an autologous bone marrow transplant (ABMT). We report here the results of a high-dose chemotherapy regime with nonpurged ABMT in 82 adult patients in fi...
متن کاملTandem High-Dose Chemotherapy and Autologous Stem Cell Transplantation for Atypical Teratoid/Rhabdoid Tumor
PURPOSE We prospectively evaluated the effectiveness of tandem high-dose chemotherapy and autologous stem cell transplantation (HDCT/auto-SCT) in improving the survival of patients with atypical teratoid/rhabdoid tumors while reducing the risks of late adverse effects from radiotherapy (RT). MATERIALS AND METHODS For young children (< 3 years old), tandem HDCT/auto-SCT was administered after ...
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ژورنال
عنوان ژورنال: The Japanese Journal of Urology
سال: 1990
ISSN: 0021-5287,1884-7110
DOI: 10.5980/jpnjurol1989.81.1473